hi, Benno, how are you?

There are some data protection issues & it's essential to let customers know what you're doing in your privacy policy. Here's the relevant section from Last Minute:

"For any of the above purposes we may send your information internationally including to countries outside the EEA. Some of these jurisdictions offer differing levels of protection of personal information, not all of which may be as high as the UK. Beginning 1 June 2002, the personal information that you submit to us through the lastminute.com site will be collected, stored and processed at our third party service provider’s data centre in the United States. The United States has data protection laws that are different and/or less stringent than those in the UK. We will, however, ensure that your personal information is kept confidential and secure, and that the appropriate technical and organisational measures, to prevent unlawful or accidental destruction, accidental loss, unauthorised disclosure or access or other unlawful forms of processing, are implemented."

It's worth chatting to your legal person about this as they'll no doubt have experience of this & know what else you need to do.

As for other issues, there are two small ones I can think of:

1. Speed of data transfer (only really an issue if you're sending a lot & you're on a slower server/link. try & test this first though - maybe browse some heavier sites hosted at the location you're looking at? Here's an older e-consultancy thread talking about this)
2. Appearing in Google's Pages From The UK (there are also several threads on this here at e-consultancy)
   

daniel